COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 3rd May 2020. As a result, our offices will now be closed till 3rd May 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details. editor@innovativepublication.com, rakesh.its@gmail.com, Mob. 8826373757, 8826859373, 9910947804


Print ISSN:-2394-546X

Online ISSN:-2394-5478

CODEN : IJMR06

Current Issue

Year 2020

Volume: 7 , Issue: 1

Article Access statistics

Viewed: 676

Emailed: 0

PDF Downloaded: 207

Indian Journal of Microbiology Research


Musculoskeletal tuberculosis - A diagnostic dilemma: Clinico-bacteriological study among patients attending tertiary heath care centre in North Eastern India


Full Text PDF Share on Facebook Share on Twitter


Author Details : Vikramjeet Singh, Anil Chandra Phukan, Bhaskar Borgohain

Volume : 5, Issue : 1, Year : 2018

Article Page : 126-131


Suggest article by email


Abstract

Introduction and Objectives: Clinicians consider musculoskeletal tuberculosis as diagnostic dilemma because diagnosis frequently gets delayed due to its varied clinical presentation, false negative results on smear microscopy and less sensitivity on culture methods (20-40%). The main objectives were to know the prevalence of musculoskeletal tuberculosis (TB) among patients attending NEIGRIHMS and to understand clinical bacteriological profile of musculoskeletal tuberculosis using conventional and molecular laboratory diagnostic methods.
Materials and Methods: In this study, a total of fifty two clinical specimens like pus swab, ultrasonography guided (USG) pus aspiration, synovial fluid and bone biopsy of newly suspected musculoskeletal tuberculosis patients were evaluated for microscopy, culture and molecular detection of M. tuberculosis.
Results: The study reveals prevalence of 46.2% musculoskeletal tuberculosis among the clinically suspected patients. The most commonly involved sites in suspected musculoskeletal tuberculosis were hip joint (23.1%). USG guided pus comprises only 26.9% of the samples collected, however, yield of M. tuberculosis from them were 71%. PCR detected the maximum number of cases of musculoskeletal tuberculosis 24 (46.2%) followed by culture method 13 (25%) and smear microscopy 1 (1.92%).
Conclusion: This observation will help guiding clinicians in effective management of musculoskeletal tuberculosis cases because delayed diagnosis and treatment in musculoskeletal TB results in poor outcome.

Keywords: Extrapulmonary tuberculosis, Osteoarticular, Polymerase Chain reaction.

Doi : 10.18231/2394-5478.2018.0026

How to cite : Singh V, Phukan A C, Borgohain B, Musculoskeletal tuberculosis - A diagnostic dilemma: Clinico-bacteriological study among patients attending tertiary heath care centre in North Eastern India. Indian J Microbiol Res 2018;5(1):126-131

Copyright © 2018 by author(s) and Indian J Microbiol Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (creativecommons.org)