COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 14th April 2020. As a result, our offices will now be closed till 14th April 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details. editor@innovativepublication.com, rakesh.its@gmail.com, Mob. 8826373757, 8826859373, 9910947804

Article view: 453

Article download: 181

Indian Journal of Microbiology Research


Emergence of non albicans Candida in a tertiary care hospital of north In-dia


Full Text PDF Share on Facebook Share on Twitter


Author Details : Manmeet Gill, Sarabjeet Sharma, Ashish Khanna

Volume : 5, Issue : 2, Year : 2018

Article Page : 244-248


Suggest article by email


Abstract

Introduction: Over past few years, a dramatic increase in the incidence of infections caused by Candida species is seen, which has been attributed to increased number of immunocompromised patients, widespread use of broad spectrum antibiotics, long term use of corticosteroids and immunosuppressive drugs, prolonged hospital stay and use of advanced life support systems
Aims and Objectives:To determine the incidence of Candida infections among patients admitted to a tertiary care teaching hospital of north India, characterise Candida isolates upto to specie level and also to evaluate presence of any drug resistance among these strains.
Material and Methods:Present study was a hospital based prospective study carried out in the Department of Microbiology, of a tertiary care hospital in north India, over a period of one year from June 2016 to May 2017. For all Candida isolates obtained from various clinical samples, identification to the species level and anti-fungal susceptibility testing was done by automated Vitek 2 compact system (Biomerieux). Results were interpreted as per CLSI guidelines.
Results:A shift of trends from Candida albicans to non albicans Candida was observed as out of total 56 isolates, the number of Candida albicans isolates was 16 (28.6%) and non-albicans Candida was 40 (72.4%). Anti-fungal susceptibility test results showed high susceptibility to Voriconazole and Amphotericic B. Only 5.35% (3/56) of Candida isolates showed resistance.
Conclusions: Since non albicans Candida has emerged as an important nosocomial pathogen and these species are intrinsically resistant to some of the commonly used anti fungal drugs so anti-fungal susceptibility should be routinely performed to improve the treatment outcomes, for the benefit of the patient.

Keywords: Candida albicans, Shift, non albicans Candida, Anti fungal susceptibility testing

Doi : 10.18231/2394-5478.2018.0051

How to cite : Gill M, Sharma S, Khanna A, Emergence of non albicans Candida in a tertiary care hospital of north In-dia. Indian J Microbiol Res 2018;5(2):244-248

Copyright © 2018 by author(s) and Indian J Microbiol Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)