COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 3rd May 2020. As a result, our offices will now be closed till 3rd May 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details.,, Mob. 8826373757, 8826859373, 9910947804

Print ISSN:-2394-546X

Online ISSN:-2394-5478


Current Issue

Year 2020

Volume: 7 , Issue: 1

Indian Journal of Microbiology Research

Clinico - mycological study on superficial fungal infections in tertiary care hospital and a profile of their antifungal susceptibility pattern

Full Text PDF

Author Details: Kumaran Ganesan, AS Shameem Banu, Riswana Jasmine

Volume : 4

Issue : 2

Online ISSN : 2394-5478

Print ISSN : 2394-546X

Article First Page : 167

Article End Page : 170


Background: Superficial fungal infections are one among the most common fungal diseases in the world. Dermatophytosis is common in tropical countries like India and may reach epidemic proportions in areas with high rate of humidity and over population and poor hygienic conditions.
Material & Method: The present study was undertaken to isolate, identify and determine the antifungal susceptibility of various fungal agents causing mycoses among the patients attending the Dermatology outpatient (OP) Chettinad hospital and research institute. Clinical samples from 200 patients were subjected to KOH examination and culture isolation. Causative agents were identified by colony morphology, pigment production and by microscopic examination. Antifungal susceptibility testing was done by broth dilution detecting the minimum inhibitory concentration.
Result: In total of 200 specimens cultured 98 dermatophytes were isolated and 12 non dermatophytic fungus were isolated which includes 5 isolates of Candida albicans and 7 isolates of Candida non albicans. Trichophyton mentagrophyte was the predominant dermatophyte isolate found in 62 cases of dermatophytosis followed by T.rubrum 22. This study showed among 98 isolates of dermatophytes, lowest value of MIC sensitivity was recorded in terbinafine as 0.03μg/ml and highest value was recorded with fluconazole 32μg/ml.
Conclusion: It is concluded that causative fungal agent for cutaneous mycoses in addition to dermatophytes and non-dermatophytes fungi Candida species also play an important role. Terbinafine was found to be the most potent drug for treating dermatophytic infections.

Dermatophytes, T.mentagrophytes, T.tonsurans, M.canis

Doi No:-10.18231