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IP Indian Journal of Neurosciences

Factors associated with enlargement of hematoma in patients with primary intracranial hemorrhage

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Research Article

Author Details : Alok Verma, Saurabh Agarwal, Manish Singh*

Volume : 5, Issue : 4, Year : 2019

Article Page : 181-188

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Introduction: This study is done to evaluate the role of different clinical factors in hematoma enlargement,
especially severe hypertension during the early phase of spontaneous ICH.
Materials and Methods: All patients with spontaneous intracranial hematoma who were of > 18 years in
age, presented within 24 hour of onset, were enrolled for this study. Repeat CT scan was done within 24 -
48 hours after 1st scan.
Results: 88 patients were enrolled and among them, 11 (12.5%) had >20% enlargement in the size of
the hematoma on the second CT. The Mean increase in the size of hematoma was 19.8 11.4 ml (47.3
27.2 %). Progression of symptom after onset and after admission, lower GCS (< 8> from onset to CT < 6> the enlargement of the hematoma. Mean systolic BP at admission > 200 mm Hg was present in a higher
proportion of patients with hematoma enlargement.
Conclusion: The present study showed that patients of spontaneous ICH presenting within 6 hours with
higher NIHSS, low GCS (GCS <8> hematoma enlargement. SBP >200 mm of Hg at admission may be a potential risk factor.
( Hematoma enlargement, NIHSS =National Institute Health Stroke Scale score, GCS =Glasgow Coma
Scale, MAP=mean arterial pressure)

Keywords: ute Health SHematoma enlargement, National Instittroke Scale score, Glasgow Coma Scale

Doi : 10.18231/j.ijn.2019.029

How to cite : Verma A , Agarwal S , Singh M , Factors associated with enlargement of hematoma in patients with primary intracranial hemorrhage. IP Indian J Neurosci 2019;5(4):181-188

Copyright © 2019 by author(s) and IP Indian J Neurosci. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (