COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 3rd May 2020. As a result, our offices will now be closed till 3rd May 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details.,, Mob. 8826373757, 8826859373, 9910947804

Print ISSN:-2581-8236

Online ISSN:-2581-916X


Current Issue

Year 2020

Volume: 6 , Issue: 1

Article Access statistics

Viewed: 177

Emailed: 0

PDF Downloaded: 96

IP Indian Journal of Neurosciences

Recuperative properties of Moringa Oleifera seed oil on cadmium and alcoholic beverage induced frontal cortex damage in Wistar Rats

Full Text PDF Share on Facebook Share on Twitter

Research Article

Author Details : Omotoso Olusegun Dare*, Agbana Busayo E, Olorunnado Samson E

Volume : 5, Issue : 4, Year : 2019

Article Page : 214-219

Suggest article by email


Aim: The aim of this study was to investigate the ameliorative effects by the intervention of Moringa
Oleifera seed oil on the damage to frontal cortex of rats by cadmium and herbal alcoholic beverage.
Materials and Method: Eighty Wistar rats (73-151g,n=10)grouped as follows: A Control;B1(Cadmium)
;B2(Cadmium+Moringa seed oil) ;C1(Herbal alcoholic Beverage);C2(Herbal alcoholic Beverage +moringa
seed oil);D(Cadmium +Herbal alcoholic beverage);E(Cadmium+Herbal alcoholic beverage+Moringa seed
oil) and F(Moringa seed oil) for four weeks followed by histological studies.
Results: The histoarchitecture of the frontal cortex was characterized by pyknosis of nuclei which resulted
in dissolution of Nissl substance. Activation of astrocytes were evidence in group B1, B2, C1, C2 and D
which were exposed to cadmium and HAB while those of groups B2, C2 and E showed ameliorative effect
that were evident in reduction in pyknotic neurons and reduction of activated astrocytes.
Conclusion: Based on the results, it can be deduced that Moringa Oleifera seed oil has neuroprotective

Keywords: Cadmium, frontal cortex, Moringa, Beverage, Nissl substance

Doi : 10.18231/j.ijn.2019.035

How to cite : Dare O O, Agbana Busayo E, Olorunnado Samson E, Recuperative properties of Moringa Oleifera seed oil on cadmium and alcoholic beverage induced frontal cortex damage in Wistar Rats. IP Indian J Neurosci 2019;5(4):214-219

Copyright © 2019 by author(s) and IP Indian J Neurosci. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (