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IP Indian Journal of Neurosciences


A study on cognitive status in chronic kidney patients on dialysis


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Research Article

Author Details : V N Madhava Rao*, B L Narsimha Reddy, Malleshwar Bottu, V Chandrasekhar

Volume : 5, Issue : 4, Year : 2019

Article Page : 246-253


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Abstract

Introduction: Cogitive impairment is common in uremia and diabetes mellitus. Cognitive impairment
affects the activities of daily living in most of chronic kidney disease patients. As per literature, cognitive
impairment is less common in non-diabetic than diabetic of chronic kidney disease. There is sparse data
regarding incidence and pattern of cognitive impairment in chronic kidney disease patients with regard to
mode of dialysis either hemodialysis or peritoneal dialysis.
Aim and Objectives: Aim : To estimate the pattern and prevalence of cognitive impairment in chronic
kidney patients on dialysis.
Objectives: 1) To compare the pattern of cognitive impairment between hemodialysis and peritoneal
dialysis patients.
2) T o study the impact of glycemic status on cognitive impairment in chronic kidney disease patients.
Material and Methods: A prospective cross-sectional observational study conducted at MGM
hospital/Kakatiya medical college during May 2016 through December 2017 on chronic dialysis patients
who fulfilled the inclusion and exclusion criteria. All the cases were subjected to Cognitive assessment by
applying ACE- R adapted to Telugu speaking people.
Results: 1) In our study the prevalence of dementia and mild cognitive impairment (MCI) were 47% &
21% respectively.
2) Among 47 dementia patients 31(66%) were diabetic, 25(53%) were undergoing hemodialysis and
22(46%) were undergoing peritoneal dialysis.
3) The pattern of cognitive decline was memory (89%), language (78%), visuospatial (68%), attention
(57%), and fluency (57%).
Conclusions: Present study highlighted not only the burden of cognitive decline in the dialysis patients
where hemodialysis and presence of diabetic were significantly associated with dementia.

Keywords: ACE-R: Addenbrooke’s cognitive, examination-revised, chronic kidney disease, Dementia, hemodialysis, MCI: mild cognitive impairment, peritoneal dialysis

Doi : 10.18231/j.ijn.2019.041

How to cite : Rao V N M, Reddy B L N, Bottu M , Chandrasekhar V , A study on cognitive status in chronic kidney patients on dialysis. IP Indian J Neurosci 2019;5(4):246-253

Copyright © 2019 by author(s) and IP Indian J Neurosci. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (creativecommons.org)