IP Indian Journal of Neurosciences

Augmentation Strategy with Low Dose Aripiprazole in Long Standing Persistent Depressive Disorder: A Case Report from India

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Author Details: Sompur V Sushil K.

Volume : 2

Issue : 1

Online ISSN : 2581-916X

Print ISSN : 2581-8236

Article First Page : 31

Article End Page : 33


Depression is the leading cause of disability among women in the world, frequently under recognized and inadequately treated. In spite of the different antidepressants available at the present time, they are far from ideal and show a similar slow & frequently incomplete response. This case report describes a 75 yr. old woman with persistent depressive disorder with intermittent major depressive episodes lasting for almost 40 years who was inadequately treated. It highlights the effectiveness of augmentation of low dose Aripiprazole in long standing persistent depressive disorder with intermittent major depressive episodes. After optimization of treatment with a known anti-depressant the augmentation strategy can produce a therapeutic response as early as 2 weeks with more than 50% reduction in symptoms on PHQ-9 scores.

Key words:
Augmentation strategy, Aripiprazole, Persistent depressive disorder, Recurrence

Doi No:-10.18231