COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 14th April 2020. As a result, our offices will now be closed till 14th April 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details. editor@innovativepublication.com, rakesh.its@gmail.com, Mob. 8826373757, 8826859373, 9910947804

Article view: 118

Article download: 122

Indian Journal of Obstetrics and Gynecology Research


A comparative study of the accuracy of the spot Protein-Creatinine Ratio (PCR) vs 24 hours urine collection for detection of proteinuria in pre- eclamptic patients and its effect maternal and fetal outcomes


Full Text PDF Share on Facebook Share on Twitter


Research Article

Author Details : Hemant Deshpade, C S Madkar*, Gurkiran Kaur, Swarna Gupta

Volume : 7, Issue : 1, Year : 2020

Article Page : 16-22


Suggest article by email


Abstract

Introduction: Proteinuria is a major component of preeclampsia. Urine protein measurement after 24-hour
urine collection is the traditional standard method for the detection of proteinuria. It is time-consuming.
As an alternative, spot sampling for a urine protein to creatinine ratio (PCR) ratio has been investigated.
Aim & Objectives: To determine the accuracy of the spot protein- creatinine ratio in comparison with 24
hours urine collection for detection of proteinuria in pre- eclamptic patients.
Materials and Methods: A hospital based prospective study was conducted with 120 patients to assess
the quantification of proteinuria in preeclamptic patient and comparing the two methods i.e. 24-hr urine
protein levels and random protein creatinine ratio conducted at tertiary care centre.
Results: There was a good positive statistical correlation between 24-hour total urinary protein level and
spot protein: creatinine ratio with a correlation coefficient (r) of 0.769.Conclusion: Random and spot urine
protein creatinine ratio can predict with high accuracy the amount of 24- hour urine protein excretion. The
urine PCR is reliable, relatively faster and accurate for proteinuria and can correlate well with 24-hour
urinary protein excretion which is gold standard.

Keywords: Preeclampsia,Proteinuria, 24-hour urine collection, Spot urine PCR (protein to creatinine ratio)

Doi : 10.18231/j.ijogr.2020.004

How to cite : Deshpade H, Madkar C S, Kaur G, Gupta S, A comparative study of the accuracy of the spot Protein-Creatinine Ratio (PCR) vs 24 hours urine collection for detection of proteinuria in pre- eclamptic patients and its effect maternal and fetal outcomes. Indian J Obstet Gynecol Res 2020;7(1):16-22

Copyright © 2020 by author(s) and Indian J Obstet Gynecol Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)