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Indian Journal of Obstetrics and Gynecology Research

Comparison between extra amniotic saline infusion vs PGE2 for cervical ripening – a randomised trial

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Author Details : Dhananjaya BS, Omkara Murthy K, Anitha MS, Chaitra R, Rajesh SS

Volume : 3, Issue : 4, Year : 2016

Article Page : 322-325

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Background: Induction of labour is one of the most important interventions done in obstetric practice. To compare between extra amniotic saline infusion and PGE2 for cervical ripening. Extra amniotic saline infusion achieved a greater number of favourable Bishop score and lead to shorter induction delivery interval and less painful, less chance failure of induction with good perinatal outcome. Hence EASI is one of the effective, safe and economical method of induction of labour.
Objective: To compare the induction delivery interval between the two groups, the mode of delivery in two groups and to compare the APGAR score in both the groups.
Materials and Methods: A prospective study of all case of  pregnant women who got admitted to labour ward requiring induction of  labour were randomly assigned to EASI or PGE2  between October 2010 to April 2012.
The study was done in 80 women counseling was done regarding both the methods of induction and the choice was given them. 40 women were assigned to extra amniotic saline infusion and 40 women assigned to PGE2 were randomly recruited.
Results: results were comparable in terms of maternal age, indication for induction in majority of cases, pre induction bishop score, mode of delivery, intrapartum complications and side effects, neonatal complications, pain scoring by VAS and APGAR score.
The mean post induction Bishop score was higher in extra amniotic saline infusion group by an average of 10. The induction delivery interval was prolonged by an average of 3 hrs in PGE2 gel group. EASI was less painful compared to PGE2.
Conclusion: For pre induction cervical ripening the extra amniotic saline infusion is valid alternative for the application of intracervical PGE2 gel. The induction delivery was prolonged (an average of 3 hrs) in PGE2 gel group.

: Extra amniotic saline infusion(EASI), PGE2 gel, Induction of labour, Induction-delivery interval, Bishop score, Cervical ripening.

How to cite : Dhananjaya Bs, Omkara Murthy K, Anitha Ms, Chaitra R, Rajesh Ss, Comparison between extra amniotic saline infusion vs PGE2 for cervical ripening – a randomised trial. Indian J Obstet Gynecol Res 2016;3(4):322-325

Copyright © 2016 by author(s) and Indian J Obstet Gynecol Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (