COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 3rd May 2020. As a result, our offices will now be closed till 3rd May 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details.,, Mob. 8826373757, 8826859373, 9910947804

Print ISSN:-2394-2746

Online ISSN:-2394-2754


Current Issue

Year 2020

Volume: 7 , Issue: 1

Article Access statistics

Viewed: 511

Emailed: 0

PDF Downloaded: 252

Indian Journal of Obstetrics and Gynecology Research

The diagnostic accuracy of spot urine protein-creatinine ratio (UPCR) in quantification of proteinuria in women with preeclampsia

Full Text PDF Share on Facebook Share on Twitter

Research Article

Author Details : Dasaripalli Bharathi, Sabita P*, Nina V Kate

Volume : 6, Issue : 2, Year : 2019

Article Page : 185-191

Suggest article by email


Introduction: Estimation of urinary excretion of protein is done by the standard method of collection of urine over 24- hours and the test sample is taken from this collection. Because of its technical difficulty there is the necessity to use quick, convenient and reliable method which is well correlates with 24-h urine protein.
Aim: This study is carried out to compare the dipstick method and spot urine protein creatinine ratio (UPCR) with that of 24-h urine protein (24HUP) and also to determine the role of proteinuria in predicting the pregnancy outcome in preeclamptic patients.
Materials and Methods: We conducted this prospective analytical study in 209 antenatal women in whom 52 were with gestational hypertension and 157 were with preeclampsia. Pearson’s correlation coefficient revealed the strength of correlation while the p value less than 0.05 was considered to be statistically significant. Receiver-operator curve (ROC) was plotted to find the cut-off value of UPCR and dipstick in detecting significant proteinuria (?300mg/day).
Results: The value of UPCR strongly correlated with 24-h urine protein (r=0.941, p<0>The cut-off value of 0.25 by UPCR method was considered as significant proteinuria. A strong positive correlation was found between 24HUP test and dipstick test (r=0.759, p<0>
Conclusions: Spot UPCR can be used as a rapid and reliable alternative method to 24-h urine protein in preeclamptic patients.

Keywords: Preeclampsia, Sspot UPR, 24-h urine protein and dipstick method.

Doi : 10.18231/j.ijogr.2019.043

How to cite : Bharathi D , Sabita P, Kate N V, The diagnostic accuracy of spot urine protein-creatinine ratio (UPCR) in quantification of proteinuria in women with preeclampsia. Indian J Obstet Gynecol Res 2019;6(2):185-191

Copyright © 2019 by author(s) and Indian J Obstet Gynecol Res. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (