COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 14th April 2020. As a result, our offices will now be closed till 14th April 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details. editor@innovativepublication.com, rakesh.its@gmail.com, Mob. 8826373757, 8826859373, 9910947804

Article view: 76

Article download: 75

International Journal of Oral Health Dentistry


Polymerase chain reaction (PCR) – A review with its pertinency to dentistry


Full Text PDF Share on Facebook Share on Twitter


Review Article

Author Details : Sumit Kumar Yadav, Achla Bharti Yadav*, Neal Bharat Kedia, Gunjan Kedia, Kunal Kumar

Volume : 5, Issue : 4, Year : 2020

Article Page : 184-190


Suggest article by email

Abstract

Advances in molecular technologies over recent years have a profound impact on diagnostic pathology. These techniques utilize DNA, RNA and enzymes that interact with nucleic acids to understand biology at a molecular level. They will also provide a complementary approach to traditional methods of histopathological analysis in the future. Various molecular techniques are now being widely used throughout the world including polymerase chain reaction (PCR), hybridization methods, flow cytometry, tissue microarray and laser capture microdissection (LCM). Among these PCR is one of the most common diagnostic modality with high specificity, sensitivity and variety of applications. It will significantly impact three major areas: specific diagnosis, prognosis determination and prediction of response to therapy. Therefore, it has a great potential to become a standard procedure in diagnostic surgical pathology. The application of PCR in the context of dentistry is also presented here, along with the basics of PCR and its fundamental aspects.

Keywords: Applications, Dentistry, Inhibitors, Oral cancer, Polymerase Chain reaction, Tumor biology.

Doi : 10.18231/j.ijohd.2019.042

How to cite : Yadav S K, Yadav A B, Kedia N B, Kedia G, Kumar K, Polymerase chain reaction (PCR) – A review with its pertinency to dentistry. Int J Oral Health Dent 2020;5(4):184-190

Copyright © 2020 by author(s) and Int J Oral Health Dent. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)