COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 3rd May 2020. As a result, our offices will now be closed till 3rd May 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details. editor@innovativepublication.com, rakesh.its@gmail.com, Mob. 8826373757, 8826859373, 9910947804


Print ISSN:-2395-1354

Online ISSN:-2395-1362

CODEN : IJOSHC

Current Issue

Year 2020

Volume: 6 , Issue: 1

Article Access statistics

Viewed: 618

Emailed: 0

PDF Downloaded: 265

Indian Journal of Orthopaedics Surgery


Vitamin D deficiency showed association with knee osteoarthritis in Tamilnadu population – A pilot study


Full Text PDF Share on Facebook Share on Twitter


Author Details : Regupathy Annamalai, Amar Nagesh Kumar

Volume : 4, Issue : 1, Year : 2018

Article Page : 1-6


Suggest article by email


Abstract

Introduction: Aim of the study is to measure serum 25 – hydroxy vitamin D levels in patients with knee osteoarthritis in comparison with age matched healthy controls and also to assess the association of 25-OH vitamin with osteoarthritis.
Materials and Methods: The study population consists of 240 patients divided into two groups, Group 1 and Group 2. Group 1 with 120 subjects with clinical features of knee osteoarthritis served as controls and Group 2 consists of 120 patients of patients diagnosed with knee osteoarthritis. Serum 25-OH vitamin D was measured in all the participants by the ELFA method and concentrations <10ng/ml was considered as deficient.
Results: In Group 1, 57(46.5%) were males and 63 (53.5%) females, while in Group 2, 57(45.5%) were males and 63 (54.5%) females. Distribution of vitamin D status according to age, BMI and gender was also made and compared between the groups. Number of patients <60 years were 55 and 56 respectively in Group 1 and Group 2. Serum 25-OH vitamin D deficiency was observed in 67(55.8%) patients in Group 2 versus 15(12.5%) of Group B (P = 0.001). Further analysis of subgroups, revealed that the mean serum 25-OH vitamin D level in Group 2 aged <60 years was significantly lower than Group 1 (8.2 ± 1.1 vs. 9.2 ± 0.8 ng/ml, P < 0.05).
Conclusion: The present study findings showed a significant association between serum 25-OH vitamin D deficiency and in patients with knee osteoarthritis aged < 60 years. Screening of serum 25 – OH vitamin D measurement in patients with symptoms suggestive of knee osteoarthritis is recommended as it showed association with knee osteoarthritis.

Keywords: 25 – OH Vitamin D, Osteoarthritis, Body mass index, Age, Knee joint pain.

Doi : 10.18231/2395-1362.2018.0001

How to cite : Annamalai R, Kumar A N, Vitamin D deficiency showed association with knee osteoarthritis in Tamilnadu population – A pilot study. Indian J Orthop Surg 2018;4(1):1-6

Copyright © 2018 by author(s) and Indian J Orthop Surg. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (creativecommons.org)