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International Journal of Pharmaceutical Chemistry and Analysis


Biological evaluation of 2-Arylidene-4-(substituted aryl) but-3-en-4-olides


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Author Details : Asif Husain, Aftab Ahmad, Shah Alam Khan, Mymoona Akhter

Volume : 2, Issue : 3, Year : 2015

Article Page : 120-122


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Abstract

The aim of this study was to evaluate the in vitro anthelmintic activity of 2-Arylidene-4-(substituted aryl) but-3-en-4-olides (I-IX) against Indian earthworm i.e. Pheretima posthuma. The anthelmintic activity of nine butenolide derivatives was determined by recording the mean paralyzing and death times of the worms at concentration of 2 mg/mL. The results indicated that few of the tested butenolide derivatives possess significant anthelmintic activity comparable to positive control, albendazole.

Keywords:
  Furanone, Pheretima posthuma, Anthelmintic, Albendazole

How to cite : Husain A, Ahmad A, Khan S A, Akhter M, Biological evaluation of 2-Arylidene-4-(substituted aryl) but-3-en-4-olides. Int J Pharm Chem Anal 2015;2(3):120-122

Copyright © 2015 by author(s) and Int J Pharm Chem Anal. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)