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Indian Journal of Pathology and Oncology

Retrospective analysis of the bone marrow received at a tertiary care hospital- A study of 160 cases

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Research Article

Author Details : Nidhi Vala*, C Shrinivasan

Volume : 6, Issue : 4, Year : 2020

Article Page : 530-533

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Introduction: Bone marrow examination becomes a crucial test in diagnosis of both hematological and non
hematological malignancies, when the routine peripheral blood and other laboratory tests are not conclusive
of a diagnosis.
Aim: The aim of this study was to find the indications of bone marrow and to assess the diagnostic value.
Materials and Methods: A total of 160 cases were analyzed retrospectively from January 2016 to
December 2017. All the bone marrows received at the laboratory were included in the study.
Result: The youngest patient was 2 years old and the oldest 80 years. Amongst 160 cases 89
(55.62%) were male and 71 (44.37%) were female. M: F ratio is 1.25:1. Leucocytosis was the most
common indication of bone marrow examination followed by bicytopenia and pancytopenia. Acute
leukemia was the most frequented diagnosis (13.12%) followed by idiopathic thrombocytopenic purpura
(11.25%), myeloproliferative diseases (8.12%) and myeloma (8.12%). Few of the rare diagnosis included
hemophagocytic syndrome, hypersplenism and aplastic anemia.
Conclusion: The study concludes the bone marrow examination is crucial and important in reaching a
diagnosis in most of the cryptic cases of cytopenias and unexplained leucocytosis.

Keywords: Bone marrow examination, Cytopenia, Leukemia

Doi : 10.18231/j.ijpo.2019.103

How to cite : Vala N, Shrinivasan C, Retrospective analysis of the bone marrow received at a tertiary care hospital- A study of 160 cases. Indian J Pathol Oncol 2020;6(4):530-533

Copyright © 2020 by author(s) and Indian J Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (