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Indian Journal of Pathology and Oncology

Papillary thyroid carcinoma and its variants in tertiary care hospital at rural area

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Research Article

Author Details : Amrutha Gorva, Saritha Karre*, Swarupa Ravuri, V D Praveen Kumar Gorrela, Nishant Nimmala

Volume : 6, Issue : 4, Year : 2019

Article Page : 556-560

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Papillary thyroid carcinomas constitute more than 70% of thyroid malignancies. While the most common
variants are conventional and follicular, uncommon variants such as oncocytic, diffuse sclerosing etc are
also observed. The most common etiological factor is radiation, but genetic susceptibility and other factors
can also contribute to the development of papillary thyroid carcinoma (PTC).
Aims and Objectives: The aim of our study was to analyze different variants of papillary thyroid
carcinoma at the Kamineni Institute of Medical Sciences, Narketpally. In the Nalgonda district, thyroid
carcinoma constituted 1% and 2% of all incident cancers among males and females, respectively.
Materials and Methods: Our data base included a total of 356 patients (non neoplastic 219 and neoplastic
137). Consecutive cases of papillary thyroid carcinoma admitted to the Kamineni institute of medical
sciences were 52 (9 males and 43 females) over a period of four years.
Results: The diagnosis of thyroid cancer was confirmed by fine needle aspiration cytology in most (88%)
of the cases. There was a female preponderance (9 males and 43 females). The primary modality
of treatment was surgery with total thyroidectomy being performed in 82%, while the rest underwent
hemithyroidectomy. The papillary carcinomas were sub- categorized based on the pattern. Most of the
cases were conventional type [61.52%] followed by follicular variant PTC [21.2%], encapsulated [9.6%]
and one each case of oncocytic type, Sclerosing variant, tall cell variant, PTC with anaplastic changes
[1.92%] each.
Conclusion: The purpose of this study was to review and compare the various histopathological patterns
of PTC with those of classical PTC. Different variants or histological patterns may co-exist in the same
tumor. High dietary intake of iodine was the most significant risk factor for the etiology of papillary
thyroid carcinoma in our study.

Keywords: Papillary thyroid carcinoma, Follicular variant.

Doi : 10.18231/j.ijpo.2019.109

How to cite : Gorva A, Karre S, Ravuri S, Gorrela V D P K, Nimmala N, Papillary thyroid carcinoma and its variants in tertiary care hospital at rural area. Indian J Pathol Oncol 2019;6(4):556-560

Copyright © 2019 by author(s) and Indian J Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (