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Print ISSN:-2394-6784

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Indian Journal of Pathology and Oncology


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Author Details : Pratiksha Chheda, Sandeep Warghade, Milind Chanekar, Yogita Salunkhe, Mayur Nigalye, Rajesh Bendre,

Volume : 1, Issue : 1, Year : 2014

Article Page : 37-40

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We report an Indian family case of Hb Ty Gard. A one year old male child presented with fever and

was found to have low hemoglobin. Variant hemoglobin (Hb) was incidentally detected on HPLC
electrophoresis as an unknown abnormal peak. Molecular analysis of β-globin gene showed presence of codon 124 Pro-Gln (CCA-CAA) variation or Hb Ty Gard. The family studies revealed presence of the same mutation in mother. Mutation analysis of β-globin gene serves as an important tool for confirmation of rare hemoglobinopathies.
Key Words: β-globin, β-thalassemia

How to cite : Chheda P, Warghade S, Chanekar M, Salunkhe Y, Nigalye M, Bendre R, , A RARE HEMOGLOBIN VARIANT: HB TY GARD DETECTED IN AN INDIAN FAMILY. Indian J Pathol Oncol 2014;1(1):37-40

Copyright © 2014 by author(s) and Indian J Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (