COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 3rd May 2020. As a result, our offices will now be closed till 3rd May 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details.,, Mob. 8826373757, 8826859373, 9910947804

Covid Alert

Print ISSN:-2394-6784

Online ISSN:-2394-6792


Current Issue

Year 2020

Volume: 7 , Issue: 2

Article Access statistics

Viewed: 1218

Emailed: 0

PDF Downloaded: 215

Indian Journal of Pathology and Oncology

Seroprevalence of hepatitis E virus among blood donors in tertiary care center of north Gujarat

Full Text PDF Share on Facebook Share on Twitter

Author Details : Nimisha Shethwala, Amar Shah, Venu Shah

Volume : 5, Issue : 3, Year : 2018

Article Page : 446-449

Suggest article by email


Introduction: Hepatitis E virus (HEV) is a RNA virus having single strand and spread mainly through contaminated water and food as well as through parenteral route. Very few study has been carried out in India in general public as well as voluntary blood donor to determine HEV prevalence. The prevalence of anti-HEV in India is limited and the results differ depending on the type of population, location and serological test used in the studies.
Materials and Methods: Samples from 1345 voluntary blood donations were tested in the period between November 2014 to December 2017. Samples were tested for the presence of antibody against HEV.
Results: The study population which composed of 1280 male & 65 Female voluntary blood donors. Age of study group ranged from 18 to 60 years with a mean age of 32.48 years. Overall, the harmony among the three ELISA was 92.6% corresponding to a prevalence rate of 2.75% (37/1345). The lowest anti-HEV antibody prevalence values were seen in the younger age groups while the highest prevalence rates were found in the higher age group. No significant variation in anti-HEV antibody prevalence was noticed between genders.
Conclusion: Although hepatitis E is transmitted by fecoral route, seroprevalence of anti-HEV antibody among blood donors need to be addressed using available ELISA test or Polymerase chain reaction. Blood banks in India and other developing country should consider screening for HEV, especially when blood transfusion is given to patients with low immunity or women having pregnanacy.

Keywords: Hepatitis E, Blood donor, Seroprevalence.

Doi : 10.18231/2394-6792.2018.0086

How to cite : Shethwala N, Shah A, Shah V, Seroprevalence of hepatitis E virus among blood donors in tertiary care center of north Gujarat. Indian J Pathol Oncol 2018;5(3):446-449

Copyright © 2018 by author(s) and Indian J Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (