COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 14th April 2020. As a result, our offices will now be closed till 14th April 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details. editor@innovativepublication.com, rakesh.its@gmail.com, Mob. 8826373757, 8826859373, 9910947804

Article view: 405

Article download: 204

Indian Journal of Pathology and Oncology


Diagnostic efficacy of imprint cytology and frozen section of breast lesions


Full Text PDF Share on Facebook Share on Twitter


Author Details : Chaithra H, Subhashish Das

Volume : 6, Issue : 1, Year : 2019

Article Page : 128-136


Suggest article by email


Abstract

Objective: To perform imprint cytology of operable breast masses and evaluate its accuracy in relation to histopathological diagnosis after H &E staining and to perform frozen section on operable breast masses and evaluate its accuracy after histopathological diagnosis with H &E staining.
Materials and Methods: A total of 82 surgically resected specimens were examined by both imprint cytology and frozen section and compared with histopathological sections which were considered as gold standard.
Results: Out of 82 cases 4 taken were inadequate. Total 78 cases subjected to imprint cytology which diagnosed all 43 benign lesions correctly and out of 35 malignant lesions 29 were diagnosed correctly with 6 FN results and no FP results were seen. Imprint cytology showed sensitivity, specificity and accuracy of 100%, 82.86% and 92.31% frozen section diagnosed all 43 benign lesions correctly and out of 35 malignant lesions 33 were correctly diagnosed with 2 FN results and no FP results were seen.
Frozen section showed sensitivity, specificity and accuracy of 100%, 94.29% and 97%.
Correlation of both imprint and frozen section alone showed 45 benign lesions and out of 33 malignant lesions 29 were correctly diagnosed with 4 FN results and no FP results were seen. Imprint cytology and frozen section combined efficacy showed sensitivity, specificity and accuracy of 91.84%, 100% and 94.87%.
Final correlation of both imprint cytology and frozen section with HPE showed significant association.
Conclusion: FS is superior to imprint cytology when compared with gold standard HPE in intraoperative diagnosis of breast mass lesions.

Keywords: Frozen section, Imprint cytology, Breast.

Doi : 10.18231/2394-6792.2019.0023

How to cite : Chaithra H, Das S, Diagnostic efficacy of imprint cytology and frozen section of breast lesions. Indian J Pathol Oncol 2019;6(1):128-136

Copyright © 2019 by author(s) and Indian J Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)