Print ISSN:-2393-9079

Online ISSN:-2393-9087

CODEN : IJPPTK

Current Issue

Year 2020

Volume: 7 , Issue: 1

Article Access statistics

Viewed: 1050

Emailed: 0

PDF Downloaded: 312

Indian Journal of Pharmacy and Pharmacology


Method Development and Validation for Simultaneous Estimation of Rizatriptan Benzoate and Naproxen Sodium by UV Spectrophotometric Method


Full Text PDF Share on Facebook Share on Twitter


Author Details : Varshini K, Mahaboobunnisa Md, Chandini NB, Apurupa P, Latha PM, Prasanthi T, Lakshmana Rao A

Volume : 3, Issue : 1, Year : 2016

Article Page : 1-6


Suggest article by email


Abstract

A Simple, validated, accurate and precise simultaneous UV Spectrophotometric method has been developed for the simultaneous estimation of Rizatriptan Benzoate (RIZ) and Naproxen Sodium (NAP) in pharmaceutical dosage form. Rizatriptan Benzoate exhibits absorption maximum at 282.9nm and Naproxen Sodium shows absorption maximum at 261.8nm in methanol. The Beer’s law obeyed the concentration range of 5-30µg/ml for RIZ and NAP. Mean recovery of 100.25% for RIZ and 99.2%5 for NAP respectively signifies the accuracy of the method. This method can be used for the routine simultaneous estimation of RIZ and NAP in pharmaceutical dosage forms.

Keywords:
Rizatriptan benzoate, Naproxen sodium, Estimation, Spectrophotometry, Dosage form

How to cite : Varshini K, Mahaboobunnisa Md, Chandini Nb, Apurupa P, Latha Pm, Prasanthi T, Lakshmana Rao A, Method Development and Validation for Simultaneous Estimation of Rizatriptan Benzoate and Naproxen Sodium by UV Spectrophotometric Method. Indian J Pharm Pharmacol 2016;3(1):1-6

Copyright © 2016 by author(s) and Indian J Pharm Pharmacol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (creativecommons.org)