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Indian Journal of Pharmacy and Pharmacology


Formulation and evaluation of orodispersible tablet containing piroxicam by sublimation method


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Author Details : SC Darade, PB Patil, RS Kalkotwar

Volume : 4, Issue : 2, Year : 2017

Article Page : 77-82


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Abstract

The most preferred route of administration is oral administration of any dosage form because of its self-medication, exact dose of drug and easily administration but difficulty in swallowing in geriatric patients is one important drawback of this route and mentally disturb patients. To solved this problem disintigration time of oral disintegration tablet is within 30 sec. which is disintegrate in mouth. Piroxicam with camphor as subliming agent combined to form fast dissolving tablet.wet granulation technique is used for preparation of Orodispersible tablets of Piroxicam drug. Camphor was removed from the granules by using vaccum. Then tablet were prepared and expose to vaccum. The tablet formulations were evaluated for Disintegration time, dissolution, hardness, friability, weight variation and thickness.

Keywords:
Orodispersible tablet (ODTs), Piroxicam, Subliming agent, Camphor

 

How to cite : Darade S, Patil P, Kalkotwar R, Formulation and evaluation of orodispersible tablet containing piroxicam by sublimation method. Indian J Pharm Pharmacol 2017;4(2):77-82

Copyright © 2017 by author(s) and Indian J Pharm Pharmacol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (creativecommons.org)