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Indian Journal of Pharmacy and Pharmacology


Neuropharmacological effects of Albizzia Chinensis extract


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Author Details : Naresh Gupta, Dinesh Kansal*

Volume : 5, Issue : 3, Year : 2018

Article Page : 129-134


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Abstract

Introduction: To know the Neuropharmacological effects of Albizzia chinensis extract in rats and mice.
Materials and Methods: The test compound was evaluated experimentally for its neuropharmacological activities in rats and mice. Blind neuropharmacological screening, potentiation of barbiturate hypnosis, stimulation of the central nervous system, maximal electroshock and pentylenetetrazol induced convulsions, analgesic activity were studied.
Results: The compound potentiated pentobarbital hypnosis, reduced spontaneous motor activity, antagonized amphetamine induced hyperactivity, blocked the conditioned avoidance response without affecting the unconditioned response and showed analgesic activity by the tail-flick method but not in hot plate model in the experimental animals.
Conclusion: The compound is similar to chlorpromazine and morphine.

Keyword: Saponin, Central nervous system, Animals.

Doi : 10.18231/2393-9087.2018.0028

How to cite : Gupta N, Kansal D, Neuropharmacological effects of Albizzia Chinensis extract. Indian J Pharm Pharmacol 2018;5(3):129-134

Copyright © 2018 by author(s) and Indian J Pharm Pharmacol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)