Print ISSN:-2393-9079

Online ISSN:-2393-9087

CODEN : IJPPTK

Current Issue

Year 2019

Volume: 6 , Issue: 4

Article view: 403

Article download: 189

Indian Journal of Pharmacy and Pharmacology


Hypolipidemic activity of Lannea coromandelica Houtt. leaves in Triton X-100 induced hyperlipidemic rats


Full Text PDF Share on Facebook Share on Twitter


Author Details : Galanki Vasantha, A Venkatesham*, CH Dayakar

Volume : 5, Issue : 4, Year : 2018

Article Page : 207-210


Suggest article by email


Abstract

Lannea coromandelica Houtt have multiple pharmacological activities including anti-inflammatory, aphrodisiac hypotensive, anti microbial, ulcerative stomatitis, wound healing, leprosy, gout, elephantiasis and cholera. Therefore, the present study is taken up to evaluate the hypolipidemic activity of ethanolic leaf extract of L.coromandelica. The ethanolic leaf extract was evaluated for its acute toxicity (2000mg/kg) and for hypolipidemic activity (100 and 200 mg/kg) in Triton X-100 (100mg/kg, i.p) induced model for 7 days. However, the obtained statistical data indicated a significant decrease in the total cholesterol, triglycerides, LDL cholesterol, VLDL cholesterol and increase in the HDL cholesterol, with reference to the standard drug Atorvastatin (10mg/kg,p.o). These results revealed that L. coromandelica has beneficial effect in reducing the blood lipid levels indicating its efficient hypolipidemic activity.

Keywords: Lannea coromandelica, Atorvastatin, Triton-X, Hyperlipidemia.

Doi : 10.18231/2393-9087.2018.0043

How to cite : Vasantha G , Venkatesham A, Dayakar C, Hypolipidemic activity of Lannea coromandelica Houtt. leaves in Triton X-100 induced hyperlipidemic rats. Indian J Pharm Pharmacol 2018;5(4):207-210

Copyright © 2018 by author(s) and Indian J Pharm Pharmacol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)