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IP Journal of Urology, Nephrology & Hepatology Science

A novel marker for psychogenic erectile dysfunction- Salivary alfa amylase

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Research Article

Author Details : Shivam Priyadarshi*, Megha Priyadarshi

Volume : 2, Issue : 2, Year : 2019

Article Page : 23-26

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Introduction: International index of erectile function (IIEF) is a validated self-administered tool to assess erectile function, but the results are highly variable according to patient’s mood, state of mind and attitude. They may exaggerate or undermine the real condition giving score far from reality. This can be avoided by adding some objective markers to the questionnaire in diagnosing and assessing treatment response in Erectile dysfunction (ED). Our study is aiming to identify serum cortisol, salivary amylase and salivary nitric oxide as objective markers for ED.
Material and methods: This cross sectional study was conducted among 38 patients of ED diagnosed on basis of history and IIEF. Between 8- 11am, 1 ml of peripheral blood sample for serum cortisol and one ml saliva for salivary amylase measurement was collected. Berkeley nitric oxide test strip was used for measuring salivary Nitric oxide in patients.
Results: Salivary amylase has statistically significant correlation with erectile function (EF) score (spearmen’s coefficient -0.38). Salivary cortisol was found to be negatively correlated with EF score (spearmen’s coefficient -0.15).We didn’t found any significant correlation of EF score with salivary nitric oxide levels assessed by commercially available salivary nitric oxide strips.
Conclusion: Salivary amylase is a good noninvasive objective marker in evaluating patients of stress related psychogenic erectile dysfunction. Serum cortisol is not a good indicator of chronic stressful situation like psychogenic ED. However, outcome needs to be studied in a larger sample size for better assessment of results.

Keywords: Psychogenic erectile dysfunction, Salivary alfa amylase, Erectile dysfunction marker.

How to cite : Priyadarshi S, Priyadarshi M, A novel marker for psychogenic erectile dysfunction- Salivary alfa amylase. J Urol Nephrol Hepatol Sci 2019;2(2):23-26

Copyright © 2019 by author(s) and J Urol Nephrol Hepatol Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (