COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 14th April 2020. As a result, our offices will now be closed till 14th April 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details. editor@innovativepublication.com, rakesh.its@gmail.com, Mob. 8826373757, 8826859373, 9910947804

Article view: 92

Article download: 64

IP Journal of Diagnostic Pathology and Oncology


Platelet DistributionWidth (PDW): A novel platelet marker in thrombocytosis: An insight


Full Text PDF Share on Facebook Share on Twitter


Research Article

Author Details : R Shubha Sangeetha*, Y A Manjunatha

Volume : 4, Issue : 4, Year : 2019

Article Page : 264-267


Suggest article by email

Abstract

Introduction: Automated haematology analysers measure several haematological parameters including
platelet indices importantly PDW, MPV and Plateletcrit. PDW has been receiving attention among
all platelet indices due to its usefulness for distinguishing between reactive thrombocytosis and clonal
thrombocytosis.
Objectives: 1.To compare the PDW values in Normal Individuals and in patients with thrombocytosis.
2.To analyse the utility of PDW in patients with Thrombocytosis.
Materials and Methods: T his prospective observational study was conducted in central laboratory of
Dr B R Ambedkar Medical college Hospital, a tertiary care hospital. PDW values which were obtained by
automated haematoanalyser HORIBA were tabulated and compared in 250 individuals with normal platelet
count and 250 cases of thrombocytosis. Detail analysis of PDW values were interpreted in thrombocytosis
cases to study its utility.
Results: An increase in mean PDW was observed in patients with thrombocytosis when compared with
individuals with normal platelet count. Mean PDWshowed variations in patients with thrombocytosis with
varied underlying aetiologies.
Conclusion: PDW is a simple platelet index which increases during platelet activation. PDW is more
specific marker of platelet activation since it does not increase during simple platelet swelling.

Keywords: PDW, Thrombocytosis, Variations, Reactive thrombocytosis.

Doi : 10.18231/j.jdpo.2019.055

How to cite : Sangeetha R S, Manjunatha Y A, Platelet DistributionWidth (PDW): A novel platelet marker in thrombocytosis: An insight. IP J Diagn Pathol Oncol 2019;4(4):264-267

Copyright © 2019 by author(s) and IP J Diagn Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)