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IP Journal of Diagnostic Pathology and Oncology


Tuberculosis is still the leading cause of cervical lymphadenopathy-results of a fnac analysis in a tertiary care hospital


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Research Article

Author Details : Praba V, Sharmila G*

Volume : 5, Issue : 1, Year : 2020

Article Page : 79-82


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Abstract

Context: Cervical lymphadenopathy is a common clinical presentation. Enlarged cervical lymphnodes
could be due to variety of causes ranging from simple infectious process to malignant neoplastic conditions.
Enlarged salivary glands, thyromegaly are also mimickers for enlarged cervical lymphnodes, hence posing
diagnostic challenges clinically.In those cases, FNAC can be used as first line diagnostic test.
Aims and Objective: Purpose of this study is to utilize the usefulness of FNAC in diagnosis of both
pediatric and adult cervical lymphadenopathy and to determine the spectrum of disease distribution among
various age group patients in a tertiary care hospital.
Materials and Methods: This is a retrospective study carried out at IRT Perundurai medical college for
aperiod of two years from January 2018 to December 2019. 318 patients with enlarged neck nodes more
than6-week duration were registered and aspirated. Aspirated material was used for cytology analysis using
Haematoxylin and eosin staining, MGG staining. Special stains such as modified ziehlneelson staining for
AFB was also done. Datas were statistically analyzed.
Results: Out of 318 cases of FNAC performed in patients with enlarged cervical nodes,268 cases were
found to be adults, the most frequent cause in adults was found to be tuberculous lymphadenitis followed
by metastatic carcinomatous deposit and third most common cause was reactive lymphoid hyperplasia,
whereas in pediatric patients the most common cause was found to be reactive lymphoid hyperplasia.
Conclusion: In our study was conducted in a tertiary care hospital, the most common cause of
cervical lymphadenopathy in adults was found to be tuberculous lymphadenitis followed by metastatic
carcinomatous deposit whereas in case of pediatric cases the most common cause of cervical
lymphadenopathy is reactive lymphoid hyperplasia closely followed by tuberculous lymphadenitis. As
per WHO –Sustainable development goals-to end TB epidemic in 2030-this study alarms the increasing
burden on health sector in fighting against mycobacterium. FNAC is particularly efficacious in our country
where mycobacterial infection is endemic. Hence early intervention is mandatory.

Keywords: Cytology - FNAC - neck lymphadenopathy - tuberculosis -malignant neoplasms

Doi : 10.18231/j.jdpo.2020.015

How to cite : Praba V, Sharmila G, Tuberculosis is still the leading cause of cervical lymphadenopathy-results of a fnac analysis in a tertiary care hospital. IP J Diagn Pathol Oncol 2020;5(1):79-82

Copyright © 2020 by author(s) and IP J Diagn Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)