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Year 2020

Volume: 5 , Issue: 1

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IP Journal of Diagnostic Pathology and Oncology

Primary retroperitoneal malignant mixed Mullerian tumour: A rare case report

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Case Report

Author Details : Minnu Sibby, Kathirvelu Shanmugasamy*, Anandraj V Krishnamurthy, Sowmya Srinivasan

Volume : 5, Issue : 1, Year : 2020

Article Page : 114-117

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Malignant mixed Mullerian tumour commonly known as carcinosarcoma is a rare and aggressive biphasic
tumour with epithelial and mesenchymal components. In this reported case, a 68 year old post menopausal,
nulliparous female, presented with complaints of difficulty in breathing and abdominal discomfort. Clinical
evaluation and radiological findings were consistent with malignancy of left ovarian origin. Patient was
taken up for total abdominal hysterectomy with bilateral salpingo-oophorectomy. But intraoperatively, the
tumour was found as a single large retroperitoneal mass with no connection to ovaries or other pelvic
organs. Histopathological examination of the specimen revealed features of malignant mixed Mullerian
tumour. Immunohistochemical markers showed positivity for CK 20, Pan CK and EMA in carcinomatous
areas and vimentin in sarcomatous areas. ER and PR were found to be negative. Patient was on regular
follow-up and responded well to chemo and radiotherapy. Primaries in retroperitoneum also have poor
prognosis similar to carcinosarcomas of female genital tract.

Keywords: Biphasic tumour, Carcinosarcoma, Mixed Mullerian tumour, Retroperitoneum.

Doi : 10.18231/j.jdpo.2020.024

How to cite : Sibby M, Shanmugasamy K, Krishnamurthy A V, Srinivasan S, Primary retroperitoneal malignant mixed Mullerian tumour: A rare case report. IP J Diagn Pathol Oncol 2020;5(1):114-117

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