COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 3rd May 2020. As a result, our offices will now be closed till 3rd May 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details. editor@innovativepublication.com, rakesh.its@gmail.com, Mob. 8826373757, 8826859373, 9910947804


Print ISSN:-2581-3714

Online ISSN:-2581-3706

CODEN : IJDPA9

Current Issue

Year 2020

Volume: 5 , Issue: 1

Article Access statistics

Viewed: 392

Emailed: 0

PDF Downloaded: 138

IP Journal of Diagnostic Pathology and Oncology


A Study of atherosclerotic lesions of aorta with CD4 immunostaining


Full Text PDF Share on Facebook Share on Twitter


Author Details : Arasi Rajesh, Shantaraman, Johnsy Merla, Saravanakumari

Volume : 3, Issue : 1, Year : 2018

Article Page : 32-35


Suggest article by email

Abstract

Indian population is affected with atherosclerosis at younger age when compared to other ethnic groups. In this study histopathological grading of atherosclerotic lesions of the ascending aorta in archival specimens were performed with immunohistochemical marker for CD4+ cells in each grade of atherosclerosis. Mean ages of males and females in our study were 52.11±15.79 and 40.18±17.73 years respectively. The prevalence of various grades of atherosclerosis revealed, Grade 1 atherosclerosis in 4.90%, Grade 2 in 17.65%, Grade 3 in 32.35%, grade 4 in 28.43%, grade 5 in 13.73% cases. Grade 6 was the least common grade of atherosclerosis (1.96%). Immunohistochemistry for CD4+ was performed in 18 subjects with three cases each of grade 1 to 6. CD4+ was quantified higher in grade 1 and grade 2 lesions while progressive reduction in CD4+ positivity was seen in the advanced lesions.

Keywords: Aorta, Archival specimens, Atherosclerosis, CD4, Histopathology.

Doi : 10.18231/2581-3706.2018.0007

How to cite : Rajesh A, Shantaraman, Merla J, Saravanakumari, A Study of atherosclerotic lesions of aorta with CD4 immunostaining. IP J Diagn Pathol Oncol 2018;3(1):32-35

Copyright © 2018 by author(s) and IP J Diagn Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (creativecommons.org)