COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 3rd May 2020. As a result, our offices will now be closed till 3rd May 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details. editor@innovativepublication.com, rakesh.its@gmail.com, Mob. 8826373757, 8826859373, 9910947804


Print ISSN:-2581-3714

Online ISSN:-2581-3706

CODEN : IJDPA9

Current Issue

Year 2020

Volume: 5 , Issue: 2

Article Access statistics

Viewed: 374

Emailed: 0

PDF Downloaded: 140

IP Journal of Diagnostic Pathology and Oncology


Ultrasound/computerized tomography guided fine needle aspiration cytology of liver lesions


Full Text PDF Share on Facebook Share on Twitter


Author Details : Lekha. M.B., D.C. Prabhu, A.H. Nagarjappa

Volume : 3, Issue : 2, Year : 2018

Article Page : 68-74


Suggest article by email

Abstract

Abstract
Introduction: Malignancy in the liver, primary or metastatic, is usually inoperable at the time of diagnosis and as such, portends an ominous prognosis. A diagnostic modality such as FNAC, which offers accuracy with minimal complications and requires minimal intervention at low cost, warrants consideration early in the investigation sequence.
Objectives: The study has been undertaken to evaluate the diagnostic efficacy of ultrasonography (USG)/ computerized tomography (CT) guided FNAC in the diagnosis of liver lesions, to correlate FNAC diagnosis with histopathology wherever possible, to correlate FNAC diagnosis with radiology diagnosis and to study the cytological patterns of liver lesions.
Materials and Methods: A prospective study of 60 patients was conducted between November 2008 and October 2010. After obtaining the detailed clinical and radiological data, patients were subjected for FNAC under USG or CT guidance.
Results: Cytodiagnosis of 60 cases were categorized into 6 (10%) Non-neoplastic lesions, 53 (88.33%) malignant neoplastic lesions and 1 (1.66%) as suspicious of carcinoma. The different neoplastic lesions were 21 (39.62%) hepatocellular carcinoma, 21 (39.62%) metastatic adenocarcinoma, 6 (11.32%) metastatic poorly differentiated carcinoma and 5cases (9.43%) of unclassified malignancy. Histopathological correlation was available in 11 malignant neoplastic lesions which confirmed the diagnosis. Nineteen cases of multiple lesions described by ultrasonography and suggested differential diagnosis of metastasis and HCC proved to be metastatic in 10cases (52.63%) and HCC in 9 cases (47.36%) by cytological examination. Overall diagnostic accuracy of the FNAC of liver to detect malignant lesions was 93.75%.
Conclusion: USG/CT guided FNAC of liver permits the categorization of more frequent non-neoplastic lesions and neoplastic primary and secondary metastatic malignancy in a simple and rational manner which is helpful for the management of hepatic lesions. Ultrasound guided fine needle aspiration of liver has a promising role to play in the diagnosis and classification of liver disease than ultrasonography alone, as it requires greater degree of precision to reach diagnostic accuracy.

Keywords: Ultrasound guided, Fine needle aspiration cytology, Core needle biopsy, Hepatic lesions.

Doi : 10.18231/2581-3706.2018.0016

How to cite : M.b. L, Prabhu D, Nagarjappa A, Ultrasound/computerized tomography guided fine needle aspiration cytology of liver lesions. IP J Diagn Pathol Oncol 2018;3(2):68-74

Copyright © 2018 by author(s) and IP J Diagn Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (creativecommons.org)