COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 14th April 2020. As a result, our offices will now be closed till 14th April 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details.,, Mob. 8826373757, 8826859373, 9910947804

Article view: 368

Article download: 115

IP Journal of Diagnostic Pathology and Oncology

The histopathological spectrum of skin diseases with emphasis on clinicopathological correlation: A prospective study

Full Text PDF Share on Facebook Share on Twitter

Author Details : Priya Gupta, Veer Karuna, Kriti Grover, Monika Rathi, Nidhi Verma

Volume : 3, Issue : 2, Year : 2018

Article Page : 91-95

Suggest article by email


The spectrum of skin disease varies greatly according to the age, gender and other factors. Skin biopsies are needed in challenging clinical cases. This study was done with aim of analyzing the spectrum of skin diseases in and around Meerut and to study the correlation between clinical and final histopathological diagnosis.
This is a prospective study in which 282 skin biopsies received in Histopathology Department of LLRM Medical College Meerut, during December 2016 to December 2017. Among them 29 biopsies were inadequate and hence were not included. Remaining 253 biopsies were analyzed. The slides were stained with H & E stain.
Definite histopathological diagnosis was possible in 240 cases (94.9%). A broad spectrum of diseases were seen comprising of infectious disorders (34.6%), eczematous disorders (10.8%), papulosquamous disorders (18.3%), vesicobullous lesions (2.9%), inflammatory disorders (5.8%), pigment disorders (3.8%), degenerative diseases (1.7%), benign tumors (17.5%) and malignant tumors (4.6%).
The diversity of clinical manifestations of various skin diseases makes histopathological examination necessary for appropriate diagnosis and treatment. Histopathology also plays an important role in confirming an established clinical diagnosis. In this study, histopathology confirmed clinical diagnosis in 217 cases (85.8%), gave diagnosis different from clinical diagnosis in 23 cases (9.1%) and was noncontributory in only 13 cases (5.1%). This emphasizes that histopathological examination of skin lesions is an important tool for confirming skin diagnosis.

Keywords: Histopathological diagnosis, Infectious disorders, Papulosquamous disorders.

Doi : 10.18231/2581-3706.2018.0020

How to cite : Gupta P, Karuna V, Grover K, Rathi M, Verma N, The histopathological spectrum of skin diseases with emphasis on clinicopathological correlation: A prospective study. IP J Diagn Pathol Oncol 2018;3(2):91-95

Copyright © 2018 by author(s) and IP J Diagn Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (