COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 14th April 2020. As a result, our offices will now be closed till 14th April 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details.,, Mob. 8826373757, 8826859373, 9910947804

Article view: 320

Article download: 159

IP Journal of Diagnostic Pathology and Oncology

Study of prevalence of haemoglobin disorders in sindhi community with reference to HPLC

Full Text PDF Share on Facebook Share on Twitter

Author Details : Rajan S. Bindu, Ashok K. Methwani, Anuradha R. Bindu, Preetinanda M. Dash

Volume : 3, Issue : 2, Year : 2018

Article Page : 110-117

Suggest article by email


Introduction: Inherited haemoglobin disorders are major health problems in certain communities in different geographical areas in India. These disorders pose a huge burden on affected families physically, financially & psychologically. This study is carried out to find the Prevalence of these disorders in Sindhi community in Aurangabad city in state of Maharashtra, India.
Materials and Methods: The present cross-sectional study was undertaken among 338, apparently healthy Sindhi individuals from community in Aurangabad, Maharashtra from July 2014 to March 2017. All the samples were tested in automated hematology cell counter and then for HPLC on Bio-Rad variant classic. Various CBC parameters and Hemoglobin patterns were derived on all samples.
Result: The overall prevalence of Hemoglobinopathy was 60/338 (17.75%), comprised of 42 (12.42%) cases of BTT, 3 (0.88%) cases of BTM, 3 (0.88%) cases of SCT, 11 (3.25%) cases of Hb Q-India & One (0.29%) case of Hb Q-India+BTT.
Conclusion: Out of 338 samples, BTT and Hb Q-India were found to be more common Hb disorders in Sindhi community. Screening of community and counselling regarding the nature of these disorders are very important measures to reduce the burden of disease.

Keywords: Hemoglobin disorders, Prevalence, HPLC, β-thalassemia trait, Hb Q-India, Maharashtra, India.

Doi : 10.18231/2581-3706.2018.0024

How to cite : Bindu R S, Methwani A K, Bindu A R, Dash P M, Study of prevalence of haemoglobin disorders in sindhi community with reference to HPLC. IP J Diagn Pathol Oncol 2018;3(2):110-117

Copyright © 2018 by author(s) and IP J Diagn Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (