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IP Journal of Diagnostic Pathology and Oncology


Granulomatous inflammation in lymph nodes draining cancer: significant association or just coincidence- Diagnostic dilemma


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Author Details : Rakesh Kumar J. Ajmera*, Rohini Shewale, Hemant Kokandakar

Volume : 3, Issue : 4, Year : 2018

Article Page : 295-298


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Abstract

Causes of granulomatous inflammation are broadly divided into infective and non infective. Infective causes Includes myocbacterial, fungal or parasitic origin. Non infective includes: Foreign body granuloma, sarcoidosis, crohn’s disease. Granuloma formation seen in cancer patients may be due to previous chemotherapy or radiation therapy. However in many cases mechanism in granuloma formation and its therapeutic outcome in cancer patients remains unknown. Careful scrutiny in all cases is required where coexisting malignancy was suspected along with granuloma formation in lymph nodes draining cancers. Exact cause of granuloma formation in lymph nodes draining cancer remains unknown however immunological reaction to tumour antigens is proposed theory .These granuloma may represent impending metastasis or already existing metastasis in patients who received neoadjuvant chemoradiation.

Keywords: Granuloma, Lymph nodes, Metastasis, Chemoradiation.

Doi : 10.18231/2581-3706.2018.0060

How to cite : Ajmera R K J , Shewale R , Kokandakar H , Granulomatous inflammation in lymph nodes draining cancer: significant association or just coincidence- Diagnostic dilemma. IP J Diagn Pathol Oncol 2018;3(4):295-298

Copyright © 2018 by author(s) and IP J Diagn Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)