Print ISSN:-2581-3714

Online ISSN:-2581-3706

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IP Journal of Diagnostic Pathology and Oncology


Role of histopathology in diagnosis of leprosy- A tertiary care hospital based study


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Author Details : Mahathi Thotakura, R S A Kiran Singh*, Aruna Chintaginjala

Volume : 3, Issue : 4, Year : 2018

Article Page : 326-329


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Abstract

Introduction: Leprosy is continuous spectrum of varied clinicopathological manifestations of the disease.1 leprosy still continues to be one of major health problem due to consequent disabilities and social stigma.2,3 Timely diagnosis helps in proper treatment and reduce the chances of recurrence. It is chronic infection which affects skin and peripheral nerves.4,5 The nerve biopsies are difficult, diagnosis mainly depends upon clinical examination of skin lesions and histopathological diagnosis. Most of leprosy cases were diagnosed without histopathological examination.6 The aim of the present study was to know the Role of skin biopsy in diagnosing leprosy cases.
Materials and Methods: This was a cross sectional comparative study of skin biopsies of clinically suspected or diagnosed leprosy cases coming to the tertiary care hospital.
Results: Sixty two (62) biopsies were included in the study. All biopsies were classified histologically compared with clinical diagnosis. Out of 62 cases, BB was the main clinical diagnosis comprising 19(30.6%) followed by BL 16(25.8%), LL 11(17.8%), IND 9(14.5%), BT 5(8.1%) and TT 2(3.2%) remaining. Out of these 62 cases, 40 (64.5%) cases histopathological diagnosis were agreed with clinical diagnosis.
Conclusion: Histological examination is an important tool in the accurate diagnosis of leprosy. Indeterminate and borderline leprosy cases diagnosed on clinical grounds are difficult due to it's varied presentation and could mimic with other diseases, therefore histopathological examination is useful to confirm diagnosis and accurate typing of leprosy for proper treatment.

Keywords: Leprosy, histopathology TT-tuberculoid, BT-Borderline Tuberculoid, BB-Borderline Borderline, BL-Borderline Lepromatous, LL-Lepromatous leprosy.

Doi : 10.18231/2581-3706.2018.0065

How to cite : Thotakura M , Singh R S A K , Chintaginjala A , Role of histopathology in diagnosis of leprosy- A tertiary care hospital based study. IP J Diagn Pathol Oncol 2018;3(4):326-329

Copyright © 2018 by author(s) and IP J Diagn Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (creativecommons.org)