COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 14th April 2020. As a result, our offices will now be closed till 14th April 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details. editor@innovativepublication.com, rakesh.its@gmail.com, Mob. 8826373757, 8826859373, 9910947804

Article view: 149

Article download: 91

IP Journal of Diagnostic Pathology and Oncology


Spectrum of hepatic lesions-A histopathological study of liver biopsies


Full Text PDF Share on Facebook Share on Twitter


Author Details : Priyanka S Murgod, Preeti R Doshi*, V D Dombale

Volume : 4, Issue : 3, Year : 2019

Article Page : 200-203


Suggest article by email

Abstract

Introduction: Liver biopsy contributes greatly to the understanding of liver diseases & is considered gold
standard for evaluating liver disorders, providing information regarding diagnosis, disease progression and
response to therapy.
Objectives: 1). To study histomorphological features of liver biopsies and to correlate them with presenting
co mplaints & radiological findings. 2). To document the pattern of various hepatic lesions.
Results/Observations: A retrospective study of 66 liver biopsies during the period January 2013 to May
2015 was done. Sections were stained with H & E and examined under light microscope. Special stains
were done in specific cases.
Among these, 45 cases were males and 21 cases were females. Out of 66 cases, 24(36.3%) cases were
hepatocellular carcinoma, 13(19.69 %) cases of glycogen storage disorder, 3(4.54%) cases each of fatty
liver, hepatitis, cirrhosis & degenerative liver disease. 2(3.03%) cases of liver cell dysplasia and 1(1.51%)
case each of biliary atresia , amyloidosis, miliary tuberculosis and liver abscess. Liver biopsy was non
specific in 4(6.06%) cases & inadequate in 7(10.6%)cases.
Conclusion: Microscopic examination of liver biopsy yields a diverse range of pathological findings and
helps to uncover diseases for which specific management is indicated.

Keywords: Hepatocellular carcinoma, Glycogen Storage Disorder, Liver biopsy.

Doi : 10.18231/j.jdpo.2019.042

How to cite : Murgod P S, Doshi P R, Dombale V D, Spectrum of hepatic lesions-A histopathological study of liver biopsies. IP J Diagn Pathol Oncol 2019;4(3):200-203

Copyright © 2019 by author(s) and IP J Diagn Pathol Oncol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)