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Journal of Dental Specialities

Risk of bleeding in patients with cardiovascular disease on aspirin undergoing tooth extraction

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Author Details : Anand Mangalgi, Aafreen Aftab, Santosh Mathpathi, PavanTenglikar, Swati Devani, Nagesh Ingleshwar

Volume : 3, Issue : , Year : 2015

Article Page : 159-163

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Background and purpose: Aspirin is the most frequently used preventive and therapeutic drug for patients with cardiovascular diseases because of its antiplatelet property, which might lead to the risk of excessive bleeding during the surgery. The purpose of the study is to analyze if there is a need to discontinue low dose antiplatelet therapy before dental extraction.
Methodology: The study samples consisted of 25 patients receiving 100 milligrams of aspirin daily and were scheduled to undergo dental extractions. Each patient acted as a control for himself, wherein an extraction was performed on a patient when aspirin was not discontinued and a second extraction after discontinuing aspirin for 72 hours prior the procedure. The bleeding time, clotting time, platelet count and INR were measured preoperatively at both the appointments and the amount of blood loss during the procedure was assessed.
Results: The mean blood loss at the first appointment for the patients was 5.78 ml while it was 1.18 ml at the second appointment. The difference was statistically significant with a t – value of 3.2. However, the blood loss in patients during the first appointment was easily managed using local hemostatic measures which prevent any grave bleeding complication.
Conclusion: From the observation in this study it can be stated that the low dose aspirin therapy can be continued prior to extraction procedure in the oral cavity without the fear of excessive intra-operative and post-operative bleeding.

Key words: Cardiovascular Disease, Aspirin, Tooth Extraction, Blood Loss

How to cite : Mangalgi A, Aftab A, Mathpathi S, Pavantenglikar, Devani S, Ingleshwar N, Risk of bleeding in patients with cardiovascular disease on aspirin undergoing tooth extraction. J Dent Spec 2015;3():159-163

Copyright © 2015 by author(s) and J Dent Spec. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (