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Journal of Oral Medicine, Oral Surgery, Oral Pathology and Oral Radiology


Ewing’s Sarcoma of mandible in a pediatric patient: A case report


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Case Report

Author Details : Satish Verma*, Guru Prasad R, Neeta Sharma, Narottam Ghejta

Volume : 5, Issue : 3, Year : 2019

Article Page : 80-84


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Abstract

Ewing's sarcoma is a small round-cell malignant tumor of bones, primarily affecting children and young adults. It might be neuroectodermally derived with various degrees of differentiation of the primitive neural tissues. It has retained the most unfavourable prognosis of all primary musculoskeletal tumors, with long-term survival being less than 10%. The development of multi-disciplinary therapy with chemotherapy, irradiation and surgery, the survival rates are increased to greater than 50%. The pathognomonic translocations involving the EWS gene on chromosome 22 and an ETS-type gene, which is the Fli1 gene on chromosome 11, are implicated in more than 95% of Ewing’s sarcomas. This paper reports a rare case of ES of mandible in 8years old male patient. The patient was managed with multiagent chemotherapy, followed by surgical resection.

Keywords: Ewing’s sarcoma, Mandible, Malignant tumor, Surgery, Chemotherapy.

Doi : 10.18231/j.jooo.2019.020

How to cite : Verma S, Guru Prasad R, Sharma N, Ghejta N, Ewing’s Sarcoma of mandible in a pediatric patient: A case report. J Oral Med Oral Surg Oral Pathol Oral Radiol 2019;5(3):80-84

Copyright © 2019 by author(s) and J Oral Med Oral Surg Oral Pathol Oral Radiol. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)