COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 14th April 2020. As a result, our offices will now be closed till 14th April 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details. editor@innovativepublication.com, rakesh.its@gmail.com, Mob. 8826373757, 8826859373, 9910947804

Article view: 98

Article download: 43

Santosh University Journal of Health Sciences


Comparison of fentanyl with dexmedetomidine for smooth extubation: A clinical study


Full Text PDF Share on Facebook Share on Twitter


Research Article

Author Details : Vibhor Rai*, Mubashar Ul Islam, Sweety Malik

Volume : 5, Issue : 2, Year : 2020

Article Page : 82-85


Suggest article by email

Abstract

Introduction: In general anaesthesia, commonly due to sympathetic responses patients develop tachycardia and increased secretion and bronchospasm while extubation. Fentanyl and dexmedetomidine are well known to suppress airway reflexes during airway procedures.
Aim: This study is design to compare the effects of fentanyl 1 µg/kg and dexmedetomidine 0.75 µg/kg in attenuating airway and circulatory reflexes during emergence and extubation of the endotracheal tube.
Materials and Methods: This double-blind, randomized, controlled study was done in fifty patients undergoing surgery under general anaesthesia belonging to (ASA) physical status 1 or 2. Study drugs dexmedetomidine (Group D) & Fentanyl (Group F) was given 15 min before the end of surgery as an infusion and over 15 min post extubation. Hemodynamic parameters and patient response for laryngoscopy like respiratory pattern, airway status and oral suctioning and during extubation were graded.
Discussion: Aside from measurably huge drop in BP at 5 min of medication organization which reacted to liquid bolus in the dexmedetomidine assemble there were no unfriendly symptoms amid the examination time frame. Both groups had a similar duration of recovery from anesthesia. Dexmedetomidine before 15 minutes of extubation obtain better results. Dexmedetomidine was found to produce hypotension at 5 min of drug infusion and improved with fluid bolus; HR was stable throughout the study period.
Conclusion: Extubation quality was found to be superior in dexmedetomidine group with patients arousable and tolerating suctioning and extubation. Whereas in fentanyl group, patients were awake during extubation and had tachycardia after extubation.

Keywords: Dexmedetomidine, Fentanyl, Tracheal extubation, Bronchospasm, General anaesthesia.

Doi : 10.18231/j.sujhs.2019.017

How to cite : Rai V, Islam M U, Malik S, Comparison of fentanyl with dexmedetomidine for smooth extubation: A clinical study. Santosh Univ J Health Sci 2020;5(2):82-85

Copyright © 2020 by author(s) and Santosh Univ J Health Sci. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)