COVID-19 Update - This is to inform you that the Government of India has announced a complete lockdown in India 22nd March 2020 to 14th April 2020. As a result, our offices will now be closed till 14th April 2020 and all our employees will be working from home. Office telephones will not be answered, and therefore you are requested to direct all your queries related to manuscript submission, review process, publication etc. at below mentioned details. editor@innovativepublication.com, rakesh.its@gmail.com, Mob. 8826373757, 8826859373, 9910947804

Article view: 520

Article download: 149

Telangana Journal of Psychiatry


Biological rhythm disturbances in patients with bipolar disorder under remission


Full Text PDF Share on Facebook Share on Twitter


Author Details : Bhaskar Katram, Ch. Siva Kumar

Volume : 2, Issue : 2, Year : 2016

Article Page : 76-79


Suggest article by email

Abstract

Background: Biological rhythms are very important aspects governing the human life. The patients suffering from bipolar disorder have lot of issues which play an important role in the course of their illness. There is need to study their influence on the overall health in these patients especially who are under remission to prevent the relapse. This may help in improved compliance with better quality of living. Thus, reducing the need for hospitalizations.
Methods: 30 subjects with bipolar disorder according to ICD10 and fulfilling the criteria for remission were compared with 30 age matched normal subjects using the Biological Rhythms Interview of Assessment in Neuropsychiatry (BRIAN) to assess biological rhythm disturbance. It is an 18-item interviewer-administered instrument which allows us to investigate the main areas related to circadian rhythm disturbance (sleep/social, activities, and eating pattern) in bipolar disorder.
Results and discussion: The BRIAN (total) scores were 23.37 +/- 2.76 for the patients vs. 18.43 +/- 0.77 for controls were significant. Significant correlation was observed between total duration of illness (in years) and total number of episodes in the sample patient population. The correlation was of statistical significance with relation to age of onset (in years) with BRIAN’s Activity pattern (r=0.517, p=0.003 and Social pattern (r=0.409, p=0.025) and the BRIAN (Total) scores (r=0.486, p=0.007). The results suggest a potential association between biological rhythms and Bipolar disorder pathophysiology. There is need to for working other specific psychosocial interventions as a supplement to the psychopharmacological treatment of bipolar illness episodes.

Keywords:
Bipolar disorder, Biological rhythms, Remission

How to cite : Katram B, Kumar C S, Biological rhythm disturbances in patients with bipolar disorder under remission. Telangana J Psychiatry 2016;2(2):76-79

Copyright © 2016 by author(s) and Telangana J Psychiatry. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC BY 4.0) (creativecommons.org)