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Telangana Journal of Psychiatry

The prevalence of Post Stroke Depression (PSD) & its relationship with post stroke disability and lesion localization

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Author Details : Ankita V Patel, Prakash I Mehta, Kamlesh Patel, Sanjiv H. Prajapati

Volume : 4, Issue : 1, Year : 2018

Article Page : 22-28

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Introduction: Depression is a common neuropsychiatric sequel of stroke. PSD (Post stroke depression) can be due to psychological reaction to clinical consequences of stroke like disability or can be consequences of specific brain lesion. PSD is associated with poor long term functional and rehabilitation outcome.

  1. To determine the prevalence of PSD and its association with socio-demographical factors.
  2. To study PSD and its association with post stroke disability.
  3. To study the relationship between PSD & side and site of lesion.

Materials and Methods: Consecutive 52 patients with diagnosis of cerebro-vascular stroke were included in the study. The written informed consent was taken. Detailed socio-demographical variables, stroke related factors, medical and psychiatric history was obtained using a semi structured Performa. Neuro-imaging provided information on lesion location. Subjects were given HAM-D to assess depression and WHODAS 2.0 to assess disability.
Collected data analyzed using SPSS version 16.
Results:Of 52 patients, 38 were depressed (73.08%). The association between the disability and PSD was nearly significant. The association between PSD and side of lesion was not significant. The association between the site of lesion and PSD was significant. Association between bilateral cortical and sub cortical lesion with PSD was also found significant.
Conclusions:The results of our study show the high prevalence of PSD and its correlation with site (cortical and sub cortical) of lesions as well as severity of disability, which support biopsychosocial model of post stroke depression.

Keywords: Disability, Lesion Localization, Post stroke depression, Stroke

How to cite : Patel A V, Mehta P I, Patel K, Prajapati S H, The prevalence of Post Stroke Depression (PSD) & its relationship with post stroke disability and lesion localization. Telangana J Psychiatry 2018;4(1):22-28

Copyright © 2018 by author(s) and Telangana J Psychiatry. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (CC-BY-NC 4.0) (